Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 8/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788710 | 0.87 | ELANE (0.41) | NPC1DGAT1ELANETYRO3 | |
| SCHEMBL23068015 | 0.87 | ELANE (0.41) | NPC1DGAT1ELANETYRO3 | |
| SCHEMBL25117904 | 0.87 | ELANE (0.41) | NPC1DGAT1ELANETYRO3 | |
| SCHEMBL23068016 | 0.87 | ELANE (0.41) | NPC1DGAT1ELANETYRO3 | |
| SCHEMBL3355071 | 0.87 | NPC1 (0.45) | NPC1DGAT1ELANEPDGFRACDK5 | |
| SCHEMBL28945073 | 0.87 | DGAT1 (0.40) | NPC1DGAT1ELANEPDGFRACDK5 | |
| SCHEMBL23068023 | 0.86 | DGAT1 (0.40) | NPC1DGAT1ELANEPDGFRACDK5 | |
| SCHEMBL492060 | 0.84 | ELANE (0.41) | NPC1DGAT1ELANEPDGFRACDK5 | |
| SCHEMBL16532624 | 0.82 | ELANE (0.52) | NPC1DGAT1ELANEIDO1 | |
| SCHEMBL30379746 | 0.82 | ELANE (0.52) | NPC1DGAT1ELANEIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786673-A | CDK inhibitors and their use as medicaments | 普莱鲁德疗法有限公司 | 2022-07-22 | — | — | CN | disclosed |