⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102165 | 0.82 | — | — | |
| SCHEMBL7517764 | 0.69 | — | — | |
| SCHEMBL16670851 | 0.67 | MAPT (0.31) | — | |
| SCHEMBL103015 | 0.64 | — | — | |
| SCHEMBL103445 | 0.64 | TSHR (0.40) | — | |
| Ethyl Acetate SCHEMBL27881850 | 0.63 | — | — | |
| SCHEMBL11306264 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL1044593 | 0.61 | ALDH1A1 (0.44) | — | |
| SCHEMBL8382484 | 0.61 | ALDH1A1 (0.42) | — | |
| SCHEMBL103096 | 0.61 | BCHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250108091-A1 | PROTEIN FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING LIANGYUAN BIO-SCIENCE, LLC (CN) | 2025-04-03 | — | — | US | disclosed |
| CN-111655287-B | ILDR2 antagonists and combinations thereof | 拜耳股份公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-4470550-A1 | PROTEIN FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Liangyuan Bio-Science, LLC (CN) | 2024-12-04 | — | — | EP | disclosed |
| EP-4460527-A1 | MULTISPECIFIC CONSTRUCTS AND USES THEREOF | I-Mab Biopharma Co., Ltd. (CN) | 2024-11-13 | — | — | EP | disclosed |
| CN-118843468-A | Use of hyaluronic acid-nimesulide complexes for the treatment of local late or metastatic tumors | 爱禾公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118234503-A | Protein preparation, preparation method and application thereof | 北京良远生物医药研究有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118217245-A | Liposome nano-composition loaded with metformin and 2-deoxy-d-glucan as well as preparation method and application thereof | 苏州大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-113785067-B | Chloride-induced prokaryotic expression system | 奥瑞丽斯治疗股份公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-113214287-B | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2023-10-20 | — | — | CN | disclosed |
| CN-116549609-A | IL2 preparation, preparation method and application thereof | 北京良远生物医药研究有限公司 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023142559-A1 | PROTEIN FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京良远生物医药研究有限公司 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023131329-A1 | MULTISPECIFIC CONSTRUCTS AND USES THEREOF | I-MAB BIOPHARMA CO., LTD. (CN) | 2023-07-13 | — | — | WO | disclosed |
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4121431-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | Bugworks Research, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-115552009-A | Cytokine immunotherapy | VLP治疗公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110831629-B | Combinations comprising ABX196 for the treatment of cancer | ABIVAX公司 | 2022-08-23 | — | — | CN | disclosed |
| WO-2022149167-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2022-07-14 | — | — | WO | disclosed |