⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904590 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7451442 | 0.98 | NOS2 (0.48) | — | |
| SCHEMBL29484098 | 0.82 | IRAK4 (0.47) | — | |
| SCHEMBL1028715 | 0.82 | IRAK4 (0.47) | — | |
| SCHEMBL522024 | 0.82 | HRH4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL29898672 | 0.80 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL24916774 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL30201993 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL14082023 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL28610171 | 0.79 | HRH4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431371-B | Beta-carbolin 3,6, 9-modified derivative and preparation method and application thereof | 沈阳药科大学 | 2026-05-19 | — | — | CN | disclosed |
| EP-4573080-A1 | INDANE AND COUMARAN DERIVATIVES AS FAST SKELETAL MUSCLE MYOSIN INHIBITORS | Cytokinetics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| EP-4511112-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-119431371-A | Beta-carbolin 3,6, 9-modified derivative and preparation method and application thereof | 沈阳药科大学 | 2025-02-14 | — | — | CN | disclosed |
| US-12024506-B2 | Compounds | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-07-02 | — | — | US | disclosed |
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024040190-A1 | INDANE AND COUMARAN DERIVATIVES AS FAST SKELETAL MUSCLE MYOSIN INHIBITORS | CYTOKINETICS, INCORPORATED (US) | 2024-02-22 | — | — | WO | disclosed |
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-4121431-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | Bugworks Research, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| WO-2022149167-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2022-07-14 | — | — | WO | disclosed |