Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281296 | 1.00 | HPGD (0.48) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL697168 | 1.00 | HPGD (0.48) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL29424792 | 1.00 | HPGD (0.48) | HPGDKMT2AERCC5FEN1TSHR | |
| Water SCHEMBL8139522 | 0.98 | HPGD (0.47) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL6835363 | 0.84 | HPGD (0.42) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL6835963 | 0.84 | HPGD (0.42) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL10455866 | 0.81 | HPGD (0.46) | HPGDKMT2AERCC5FEN1MYC | |
| SCHEMBL19278858 | 0.81 | HPGD (0.46) | HPGDKMT2AERCC5FEN1MYC | |
| SCHEMBL27861393 | 0.80 | HPGD (0.46) | HPGDKMT2AERCC5FEN1TSHR | |
| SCHEMBL8193953 | 0.80 | ERCC5 (0.45) | HPGDKMT2AERCC5FEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11440882-B2 | Process for the preparation of dexmethyl phenidate hydrochloride | HARMAN FINOCHEM LIMITED (IN) | 2022-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440882-B2 | Process for the preparation of dexmethyl phenidate hydrochloride | SLC6A3, COMT, DAO | HPGD 3769/4885KMT2A 759/4885ERCC5 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.