Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 9/20 | 0.83 |
| ▸ | KDR | P35968 | 7/20 | 0.81 |
| ▸ | RET | P07949 | 3/20 | 0.80 |
| ▸ | BRAF | P15056 | 3/20 | 0.80 |
| ▸ | FLT1 | P17948 | 3/20 | 0.80 |
| ▸ | GSK3B | P49841 | 2/20 | 0.80 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.80 |
| ▸ | ABL1 | P00519 | 2/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.80 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.80 |
| ▸ | KIT | P10721 | 2/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.80 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.80 |
| ▸ | MAOA | P21397 | 2/20 | 0.80 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.80 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.80 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.80 |
| ▸ | TTK | P33981 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408499 | 1.00 | RAF1 (0.83) | RAF1KDRRETBRAFFLT1 | |
| Formamide SCHEMBL28340615 | 0.95 | RAF1 (0.79) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL3411566 | 0.92 | RET (0.81) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL10000735 | 0.92 | RAF1 (0.83) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL28948534 | 0.92 | RAF1 (0.83) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL29918250 | 0.91 | RAF1 (1.00) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL548133 | 0.91 | RAF1 (1.00) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL4609009 | 0.90 | BRAF (0.82) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL3407209 | 0.90 | RAF1 (0.80) | RAF1KDRRETBRAFFLT1 | |
| SCHEMBL4737847 | 0.90 | KDR (1.00) | RAF1KDRRETBRAFFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068620-A | Pharmaceutical composition capable of reducing generation of arylamine impurities | 天津睿创康泰生物技术有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-119792559-A | Cell-penetrating peptide modified enzyme-sensitive PDC PROTAC, and preparation method and application thereof | 西安交通大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-114767714-B | Nanometer preparation of alkynyl-modified sorafenib derivative and silver wrapped by pore material, preparation method and application thereof | 济南大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-115068620-A | Pharmaceutical composition capable of reducing generation of arylamine impurities | 天津睿创康泰生物技术有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114767714-A | Nanometer preparation of pore material wrapped alkynyl-modified sorafenib derivative and silver, preparation method and application thereof | 济南大学 | 2022-07-22 | — | — | CN | disclosed |