Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048616 | 0.78 | PDE10A (0.47) | F10SPRPIK3CDHSD11B1 | |
| SCHEMBL30949269 | 0.78 | F10 (0.44) | F10OPRM1SPRIRAK4JAK2 | |
| SCHEMBL20489182 | 0.75 | BRD4 (0.45) | F10BRD4 | |
| SCHEMBL17287034 | 0.73 | F10 (1.00) | F10BRD4 | |
| SCHEMBL18660292 | 0.73 | F10 (0.86) | F10BRD4 | |
| SCHEMBL17287032 | 0.73 | F10 (0.41) | F10SPRIRAK4CFTRBRD4 | |
| SCHEMBL27877237 | 0.72 | F10 (0.37) | F10 | |
| SCHEMBL15416710 | 0.71 | ACKR3 (0.47) | F10OPRM1IRAK4JAK2JAK1 | |
| SCHEMBL18893834 | 0.71 | CTSL (0.39) | F10OPRM1IRAK4JAK2JAK1 | |
| SCHEMBL28311500 | 0.71 | CNR1 (0.33) | F10TGFBR1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147283-B1 | HYDRAZINE COMPOUND AS BLOOD COAGULATION FACTOR XA INHIBITOR | NORTH CHINA PHARMACEUTICAL COMPANY LTD (CN) | 2022-08-17 | — | — | EP | disclosed |