Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794184 | 0.80 | PDE9A (0.32) | NOS2NOS3NOS1 | |
| SCHEMBL28518457 | 0.77 | NOS3 (0.37) | NOS2NOS3NOS1KDM4EMAPT | |
| SCHEMBL3324135 | 0.77 | KDM4E (0.37) | NOS2NOS3NOS1KDM4EMAPT | |
| SCHEMBL1199229 | 0.76 | — | — | |
| SCHEMBL12120608 | 0.75 | TSHR (0.35) | KDM4EMAPTTSHRGSK3BADORA3 | |
| Hydrochloric Acid SCHEMBL27869466 | 0.75 | KDM4E (0.37) | NOS2NOS3NOS1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1845635 | 0.75 | KDM4E (0.37) | KDM4EMAPTTSHRHRH4HRH3 | |
| Water SCHEMBL27918105 | 0.75 | NOS3 (0.36) | NOS2NOS3NOS1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL29268611 | 0.73 | KDM4E (0.36) | NOS2NOS3NOS1KDM4EMAPT | |
| SCHEMBL12123982 | 0.73 | TSHR (0.34) | NOS2NOS3NOS1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051270-A1 | 4-AMINO-IMIDAZOQUINOLINE COMPOUNDS AND USE THEREOF | Prime Reach Trading Limited (WS) | 2022-09-07 | — | — | EP | disclosed |