Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444862 | 0.88 | PKM (0.39) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL9828807 | 0.82 | MAPT (0.61) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL29452812 | 0.82 | MAPT (0.61) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL29372446 | 0.82 | MAPT (0.61) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL9828522 | 0.82 | MAPT (0.61) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL96159 | 0.82 | MAPT (0.61) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| Water SCHEMBL1095558 | 0.81 | MAPT (0.60) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL9830914 | 0.79 | PKM (0.57) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL9828624 | 0.76 | PKM (0.60) | MAPTPKML3MBTL1KDM4ECYP3A4 | |
| SCHEMBL9828717 | 0.72 | PKM (0.55) | MAPTPKML3MBTL1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781374-B2 | Synergistic mixtures | BAYER CROPSCIENCE AG (DE) | 2010-08-24 | — | — | US | claimed |