Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 13/20 | 0.58 |
| ▸ | JAK3 | P52333 | 11/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.54 |
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 2/20 | 0.54 |
| ▸ | RET | P07949 | 2/20 | 0.54 |
| ▸ | MUSK | O15146 | 1/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.51 |
| ▸ | BTK | Q06187 | 2/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | FGR | P09769 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041951 | 0.87 | NTRK1 (0.69) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL10027491 | 0.86 | JAK3 (0.58) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL422361 | 0.84 | JAK3 (0.77) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL422468 | 0.84 | JAK3 (0.77) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL23217032 | 0.83 | JAK3 (0.62) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL3420176 | 0.83 | JAK3 (0.62) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL30009943 | 0.83 | JAK3 (0.62) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL3025255 | 0.82 | JAK3 (0.54) | JAK2JAK3NTRK1FLT3CDK2 | |
| SCHEMBL588730 | 0.82 | NTRK1 (0.73) | JAK2JAK3NTRK1FLT3LCK | |
| SCHEMBL588783 | 0.82 | JAK3 (0.57) | JAK2JAK3NTRK1FLT3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-B | Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof | 休斯敦大学体系 | 2024-11-19 | — | — | CN | disclosed |
| CN-114945378-A | Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto | 休斯敦大学体系 | 2022-08-26 | — | — | CN | disclosed |