SCHEMBL29795286

SCHEMBL29795286

C=C1CCCc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.56
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
TSHR P16473 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 1/20 0.45
CES1 P23141 1/20 0.44
NOS3 P29474 2/20 0.44
DRD4 P21917 1/20 0.43
NOTUM Q6P988 1/20 0.42
CYP19A1 P11511 5/20 0.42
CYP11B1 P15538 5/20 0.42
CYP11B2 P19099 5/20 0.42
MAPT P10636 1/20 0.42
MIF P14174 1/20 0.42
G6PC1 P35575 1/20 0.40
NPY5R Q15761 1/20 0.39
BCHE P06276 2/20 0.38
NOS2 P35228 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29795287 1.00 CYP2A6 (0.56) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL1822219 1.00 CYP2A6 (0.56) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL6691916 0.95 TSHR (0.55) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL29370260 0.85 CES1 (0.54) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL66102 0.85 CES1 (0.54) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL30505637 0.82 CYP2A6 (0.68) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL3103992 0.82 CYP2A6 (0.68) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL30436320 0.79 CYP2A6 (0.65) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL9652088 0.79 CYP2A6 (0.65) CYP2A6MAOAMAOBTSHRL3MBTL1
SCHEMBL568779 0.76 TSHR (0.71) CYP2A6MAOAMAOBTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159548-A Antiviral compounds 安力高医药股份有限公司 2024-06-07 CN disclosed
EP-4366831-A1 ANTI-VIRAL COMPOUNDS Aligos Therapeutics, Inc. (US) 2024-05-15 EP disclosed
EP-4247369-A1 SPIROCYCLIC-SUBSTITUTED 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT Merck Sharp & Dohme LLC (US) 2023-09-27 EP disclosed
WO-2023283256-A1 ANTI-VIRAL COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2023-01-12 WO disclosed
CN-113880871-B Preparation method of saturated monoboron compound 中国科学院兰州化学物理研究所 2022-08-23 CN disclosed
WO-2022109487-A1 SPIROCYCLIC-SUBSTITUTED 6,7-DIHYDRO-PYRANO[2,3-D]PYRIMIDINE INHIBITORS OF KRAS G12C MUTANT MERCK SHARP & DOHME CORP. (US) 2022-05-27 WO disclosed