Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66102 | 1.00 | CES1 (0.54) | CES1MAOBCYP2A6MAOASETD7 | |
| SCHEMBL29795286 | 0.85 | CYP2A6 (0.56) | CES1MAOBCYP2A6MAOANOS3 | |
| SCHEMBL29795287 | 0.85 | CYP2A6 (0.56) | CES1MAOBCYP2A6MAOANOS3 | |
| SCHEMBL6691916 | 0.85 | TSHR (0.55) | CES1MAOBCYP2A6MAOANOS3 | |
| SCHEMBL11327557 | 0.85 | CES1 (0.50) | CES1MAOBCYP2A6MAOASETD7 | |
| SCHEMBL1822219 | 0.85 | CYP2A6 (0.56) | CES1MAOBCYP2A6MAOANOS3 | |
| SCHEMBL6006940 | 0.83 | MEN1 (0.39) | CES1MAOBCYP2A6MAOASETD7 | |
| SCHEMBL1739155 | 0.81 | CES1 (0.71) | CES1MAOBCYP2A6MAOAPDPK1 | |
| SCHEMBL30303760 | 0.81 | CES1 (0.71) | CES1MAOBCYP2A6MAOAPDPK1 | |
| SCHEMBL4039247 | 0.81 | CES1 (0.56) | CES1MAOBCYP2A6MAOASETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120041846-A | Method for preparing indane compound under electrochemical condition | 广东工业大学 | 2025-05-27 | — | — | CN | disclosed |
| US-20250002448-A1 | ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2025-01-02 | — | — | US | disclosed |
| CN-118159548-A | Antiviral compounds | 安力高医药股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117843537-A | Method for preparing beta-amino sulfide by visible light catalysis | 河南师范大学 | 2024-04-09 | — | — | CN | disclosed |
| EP-3944739-A2 | METHODS OF CARBON-CARBON BOND FRAGMENTATION | The Regents of the University of California (US) | 2022-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002448-A1 | ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | CHRNA7, CHRM1, CHRM5 | CES1 1780/4885MAOB 276/4885CYP2A6 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.