Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 14/20 | 0.97 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654951 | 0.96 | ASAH1 (0.90) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| Carbamic Acid SCHEMBL11116536 | 0.91 | ASAH1 (0.81) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| SCHEMBL3051146 | 0.90 | ASAH1 (0.80) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| Benzimidazole SCHEMBL10923154 | 0.85 | ASAH1 (0.71) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| SCHEMBL29795633 | 0.84 | ASAH1 (1.00) | ASAH1NAMPT | |
| SCHEMBL28945621 | 0.84 | ASAH1 (1.00) | ASAH1NAMPT | |
| SCHEMBL3834799 | 0.84 | ASAH1 (0.70) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| SCHEMBL13897309 | 0.83 | ASAH1 (0.70) | ASAH1ALDH1A1TSHRNPC1MAPT | |
| SCHEMBL29795398 | 0.83 | ASAH1 (0.93) | ASAH1NAMPT | |
| SCHEMBL28794797 | 0.83 | ASAH1 (0.93) | ASAH1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |