SCHEMBL3834799

SCHEMBL3834799

CCO[Si](CCCNC(=O)n1cnc2ccccc21)(OCC)OCC

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 10/20 0.70
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KMT2A Q03164 3/20 0.43
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 1/20 0.40
STAT6 P42226 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13897309 0.88 ASAH1 (0.70) ASAH1ALDH1A1NPC1MAPTHPGD
SCHEMBL10654951 0.85 ASAH1 (0.90) ASAH1ALDH1A1NPC1MAPTHPGD
SCHEMBL29795663 0.84 ASAH1 (0.97) ASAH1ALDH1A1NPC1MAPTHPGD
SCHEMBL13897306 0.82 ASAH1 (0.52) ASAH1ALDH1A1NPC1MAPTHPGD
Carbamic Acid SCHEMBL11116536 0.81 ASAH1 (0.81) ASAH1ALDH1A1NPC1MAPTHPGD
SCHEMBL3839083 0.81 LMNA (0.52) ASAH1ALDH1A1LMNA
SCHEMBL3051146 0.80 ASAH1 (0.80) ASAH1ALDH1A1NPC1MAPTHPGD
SCHEMBL28794873 0.79 ASAH1 (0.70) ASAH1NPC1HPGDRAB9AHSD17B10
SCHEMBL29795481 0.79 ASAH1 (0.70) ASAH1NPC1HPGDRAB9AHSD17B10
SCHEMBL14095318 0.78 GRIN1 (0.55) ASAH1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018137-A1 AZOLE SILANE COMPOUND, SURFACE TREATMENT SOLUTION, SURFACE TREATMENT METHOD, AND USE THEREOF Shikoku Chemicals Corporation (JP) 2016-05-11 EP disclosed
US-20090056795-A1 ELECTROLYTE FOR SOLAR CELL AND SOLAR CELL HAVING THE SAME SAMSUNG SDI CO., LTD. (KR) 2009-03-05 US disclosed
US-20090056795-A1 ELECTROLYTE FOR SOLAR CELL AND SOLAR CELL HAVING THE SAME SAMSUNG SDI CO., LTD. (KR) 2009-03-05 US disclosed