Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945638 | 1.00 | ASAH1 (0.54) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL29795389 | 0.92 | ALDH1A1 (0.48) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL28794567 | 0.92 | ALDH1A1 (0.48) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL28794739 | 0.85 | ASAH1 (0.47) | ASAH1ALDH1A1TSHRBRD4SMN1; SMN2 | |
| SCHEMBL29795526 | 0.85 | ASAH1 (0.47) | ASAH1ALDH1A1TSHRBRD4SMN1; SMN2 | |
| SCHEMBL29795435 | 0.82 | ASAH1 (0.42) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL28794606 | 0.82 | ASAH1 (0.42) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL28794723 | 0.79 | ASAH1 (0.58) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL29795413 | 0.79 | ASAH1 (0.58) | ASAH1ALDH1A1TSHRTLR8BRD4 | |
| SCHEMBL28945651 | 0.78 | CHRM4 (0.40) | ASAH1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031532-A1 | SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | Bial-R&D Investments, S.A. (PT) | 2022-07-27 | — | — | EP | disclosed |