SCHEMBL29795706

SCHEMBL29795706

COc1[nH]c(=O)ncc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.34
TP53 P04637 2/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
RAB9A P51151 2/20 0.32
RECQL P46063 1/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
XDH P47989 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390290 0.71 TP53 (0.34) KMT2AALDH1A1TP53
SCHEMBL18081882 0.70
SCHEMBL213586 0.70
SCHEMBL19363733 0.70
SCHEMBL3971478 0.67 ALDH1A1 (0.46) ALDH1A1TP53PDE3BPDE3ARAB9A
SCHEMBL18081740 0.67 KMT2A (0.36) KMT2AALDH1A1TP53RAB9ANOS3
SCHEMBL31184562 0.66 NQO2 (0.45) KMT2AALDH1A1PDE3BPDE3ARECQL
SCHEMBL14420844 0.65 NQO2 (0.39) ALDH1A1TP53PDE3BPDE3ARAB9A
SCHEMBL25647632 0.65 PDE3B (0.39) PDE3BPDE3ACYP19A1NQO2
SCHEMBL18081910 0.64 KMT2A (0.34) KMT2AALDH1A1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4065166-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS Comera Life Sciences, Inc. (US) 2022-10-05 EP claimed
EP-4605545-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. Hoffmann-La Roche AG (CH) 2025-08-27 EP disclosed
WO-2024083982-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. HOFFMANN-LA ROCHE AG (CH) 2024-04-25 WO disclosed
EP-4276197-A2 MAPPING THE LOCATION, TYPE AND STRAND OF DAMAGED NUCLEOTIDES IN DOUBLE-STRANDED DNA New England Biolabs, Inc. (US) 2023-11-15 EP disclosed
EP-3710596-B1 MAPPING THE LOCATION, TYPE AND STRAND OF DAMAGED NUCLEOTIDES IN DOUBLE-STRANDED DNA NEW ENGLAND BIOLABS INC (US) 2023-08-02 EP disclosed
US-11713484-B2 Mapping the location, type and strand of damaged and/or mismatched nucleotides in double-stranded DNA BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2023-08-01 US disclosed
WO-2023091370-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS COMERA LIFE SCIENCES, INC. (US) 2023-05-25 WO disclosed
EP-4065166-A1 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS Comera Life Sciences, Inc. (US) 2022-10-05 EP disclosed
CN-115044571-A Extreme thermophilic archaea recombinant HhH-GPD protein and preparation method and application thereof 扬州大学广陵学院 2022-09-13 CN disclosed