Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213539 | 0.83 | CYP1A2 (0.55) | KMT2AGPR142FYNSMN1; SMN2NPC1 | |
| SCHEMBL28633205 | 0.81 | KMT2A (0.55) | KMT2ASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL25200778 | 0.80 | HDAC3 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8312473 | 0.80 | KMT2A (0.56) | KMT2AGPR142FYNSMN1; SMN2ALDH1A1 | |
| SCHEMBL939191 | 0.78 | JMJD6 (0.65) | KMT2ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10389277 | 0.76 | SMN1; SMN2 (0.71) | KMT2ASMN1; SMN2MEN1ALDH1A1KDM4E | |
| SCHEMBL2829641 | 0.76 | NTRK1 (0.44) | KMT2AGPR142FYNKDM4ECREBBP | |
| SCHEMBL13996489 | 0.76 | KMT2A (0.51) | KMT2AGPR142SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13993983 | 0.76 | KMT2A (0.51) | KMT2AGPR142FYNMAPK14SMN1; SMN2 | |
| SCHEMBL17240174 | 0.75 | JMJD6 (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041231-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG (CH) | 2022-08-17 | — | — | EP | disclosed |