Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781001 | 0.82 | KMO (0.59) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL29955181 | 0.82 | KMO (0.59) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL3625688 | 0.81 | RECQL (0.56) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL29328565 | 0.80 | KMO (0.56) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL3632921 | 0.79 | FGFR1 (0.42) | RECQLKMOCYP1A2 | |
| SCHEMBL29411862 | 0.79 | FGFR1 (0.42) | RECQLKMOCYP1A2 | |
| SCHEMBL3623147 | 0.79 | RECQL (0.53) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL3621969 | 0.79 | RECQL (0.53) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL9934408 | 0.79 | RECQL (0.61) | RECQLKMOCYP1A2DAOADRA2A | |
| SCHEMBL323712 | 0.77 | RECQL (0.51) | RECQLKMOCYP1A2DAOADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022210479-A1 | USE OF AZEPANE DERIVATIVE FOR TREATMENT, AMELIORATION OR PREVENTION OF κ-OPIOID RECEPTOR-RELATED DISEASES | 日本ケミファ株式会社 | 2022-10-06 | — | — | WO | disclosed |
| CN-114761082-A | Azepane derivatives | 日本化学药品株式会社 | 2022-07-15 | — | — | CN | disclosed |