Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 2/20 | 0.63 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581979 | 0.82 | RORB (0.54) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL29865338 | 0.82 | RORB (0.54) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL15638862 | 0.81 | RORB (0.46) | RORBTGFBR1TGFBR2NPY5R | |
| SCHEMBL1968903 | 0.81 | RORB (0.52) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL15637672 | 0.80 | RORB (0.55) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL2975854 | 0.79 | CNR2 (0.46) | RORBKCNA5 | |
| SCHEMBL16046611 | 0.79 | KCNA5 (0.59) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL5093163 | 0.79 | KCNA5 (0.60) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL18447962 | 0.78 | RORB (0.49) | RORBKCNA5KCNN4TDO2IDO1 | |
| SCHEMBL31223211 | 0.78 | CNR2 (0.45) | RORBKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903238-B | Preparation method of kovar stat | 广东东阳光药业有限公司 | 2022-05-27 | — | — | CN | disclosed |