RORB — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL257142	1.00	20/20
SCHEMBL257572	1.00	20/20
SCHEMBL257434	0.79	19/20
SCHEMBL174906	0.74	19/20
SCHEMBL256651	0.79	17/20
SCHEMBL257271	0.76	17/20
SCHEMBL257203	0.67	16/20
SCHEMBL256653	0.59	16/20
SCHEMBL257608	0.83	15/20
SCHEMBL257437	0.76	15/20
SCHEMBL168526	0.70	15/20
SCHEMBL257436	0.66	15/20
SCHEMBL257269	0.60	15/20
SCHEMBL257433	0.72	14/20
SCHEMBL257615	0.72	13/20
SCHEMBL257375	0.60	13/20
SCHEMBL257432	0.74	12/20
SCHEMBL175295	0.67	12/20
SCHEMBL257260	0.60	11/20
SCHEMBL29782	0.55	10/20

Clinical trials — most relevant to RORB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of Silymarin in Rheumatoid Arthritis Patients Treated With Methotrexate	PHASE4	NOT_YET_RECRUITING
Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized)	PHASE3	UNKNOWN
Prednisolone Trial in Children Younger Than 4 Years	PHASE3	COMPLETED
Exogenous Melatonin in Intensive Care Unit Chronodisruption	PHASE3	UNKNOWN
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room	PHASE2/PHASE3	COMPLETED
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment	PHASE2	UNKNOWN
Cirmtuzumab Consolidation for Treatment of Patients With Detectable CLL on Venetoclax	PHASE2	ACTIVE_NOT_RECRUITING
Fibrates in Pediatric Cholestasis	PHASE2	COMPLETED
Preoperative Bexarotene Treatment for Cushing's Disease	PHASE1/PHASE2	UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies	PHASE2	COMPLETED
First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies	PHASE1	UNKNOWN
Meclizine for Hepatocellular Carcinoma	PHASE1	COMPLETED
Can Gluten-free Diet Prevent the Destruction of Beta-cells During Remission?	EARLY_PHASE1	UNKNOWN
A Study of RD14-01 in Patients With Advanced Solid Tumors	EARLY_PHASE1	UNKNOWN
RORC Genetic Polymorphism of Rheumatoid Arthritis	nan	COMPLETED
Effect of Liraglutide on Clock Genes	nan	UNKNOWN
Phenotypic and Functional Profile of Peripheral Blood Lymphomonocytes in Seborrheic Dermatitis.	nan	COMPLETED
Gene Expression in Chronic Venous Leg Ulcers	nan	UNKNOWN
Immunoassay and Regulation of Traditional Chinese Medicine on Cancer Patients	nan	UNKNOWN
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer	nan	UNKNOWN
Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical Outcomes	nan	COMPLETED
The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation	nan	COMPLETED
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer	nan	COMPLETED
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome	nan	COMPLETED
Involvement of Pollutants in Atopic Dermatitis and Psoriasis	nan	UNKNOWN
The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease	nan	COMPLETED
Role of Obeticholic Acid in the Patients of NAFLD With Raised ALT	nan	COMPLETED
Steroid Treatment of Idiopathic Nephrotic Syndrome	nan	COMPLETED
Mechanisms of Glucose Lowering Effect of Colesevelam HCl	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RORB binder may also engage these)

Protein	Name	Similarity
P45446	—	1.000	P45446 →
Q8R1B8	—	1.000	Q8R1B8 →
F1QLY4	—	1.000	F1QLY4 →
RORA	Nuclear receptor ROR-alpha	0.997	landscape →
P31396	—	0.997	P31396 →
P49882	—	0.997	P49882 →
P51448	—	0.997	P51448 →
P13053	—	0.996	P13053 →
P48281	—	0.996	P48281 →
Q9W785	—	0.995	Q9W785 →
P57797	—	0.994	P57797 →
P49883	—	0.994	P49883 →
A3RGC1	—	0.994	A3RGC1 →
Q28037	—	0.994	Q28037 →
Q8HYL6	—	0.994	Q8HYL6 →
O18473	—	0.994	O18473 →
O42450	—	0.994	O42450 →
VDR	Vitamin D3 receptor	0.993	landscape →
Q14541	—	0.993	Q14541 →
THRB	Thyroid hormone receptor beta	0.993	landscape →
P28700	—	0.993	P28700 →
P51128	—	0.993	P51128 →
Q9W6N4	—	0.993	Q9W6N4 →
Q6GN21	—	0.993	Q6GN21 →
Q28570	—	0.993	Q28570 →
Q21878	—	0.993	Q21878 →
P06212	—	0.993	P06212 →
O57606	—	0.993	O57606 →
Q9PTN2	—	0.993	Q9PTN2 →
Q9XSB5	—	0.993	Q9XSB5 →