SCHEMBL29797106

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.54

▸	GLP1R	P43220	11/20	0.54

▸	VIPR2	P41587	6/20	0.53

▸	VIPR1	P32241	4/20	0.53

▸	BACE1	P56817	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29836204	0.89	GLP1R (0.59)	GLP1RVIPR2VIPR1
SCHEMBL31366748	0.89	GLP1R (0.51)	GLP1RVIPR2VIPR1
SCHEMBL30252503	0.89	NPY4R (0.54)	BACE1
SCHEMBL31256985	0.89	GLP1R (0.45)	KEAP1GLP1RVIPR2VIPR1BACE1
SCHEMBL29836295	0.88	GLP1R (0.58)	GLP1RVIPR2VIPR1
SCHEMBL8427711	0.88	KEAP1 (0.56)	KEAP1GLP1RVIPR2VIPR1BACE1
SCHEMBL30168712	0.88	GLP1R (0.59)	GLP1RVIPR2VIPR1
SCHEMBL30168716	0.88	GLP1R (0.60)	GLP1RVIPR2VIPR1
SCHEMBL31183012	0.88	VIPR1 (0.62)	GLP1RVIPR2VIPR1
SCHEMBL30692675	0.88	GLP1R (0.56)	GLP1RVIPR2VIPR1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114786704-A	Active polypeptide compounds	陕西麦科奥特科技有限公司	2022-07-22	—	—	CN	claimed