SCHEMBL29797173

CCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	VIPR2	P41587	5/20	0.59

▸	VIPR1	P32241	3/20	0.59

▸	GLP1R	P43220	4/20	0.59

▸	ECE1	P42892	1/20	0.59

▸	MUS81	Q96NY9	1/20	0.59

▸	TFPI	P10646	1/20	0.58

▸	NPY5R	Q15761	3/20	0.58

▸	NPY1R	P25929	2/20	0.58

▸	NPY4R	P50391	2/20	0.58

▸	GCGR	P47871	1/20	0.56

▸	GIPR	P48546	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30176485	0.89	VIPR2 (0.61)	VIPR2VIPR1GLP1RTFPINPY5R
SCHEMBL31182584	0.88	TFPI (0.66)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL30900770	0.88	TFPI (0.66)	VIPR1GLP1RECE1MUS81TFPI
SCHEMBL30607476	0.88	TFPI (0.67)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29797052	0.87	MAPK8 (0.67)	TFPINPY5RNPY1RNPY4R
SCHEMBL38664796	0.86	VIPR1 (0.67)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL31683277	0.86	VIPR2 (0.61)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL30567756	0.85	VIPR1 (0.72)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL30495775	0.85	VIPR1 (0.70)	VIPR2VIPR1GLP1RECE1MUS81
SCHEMBL29634728	0.85	TFPI (0.61)	VIPR2VIPR1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220259267-A9	Inhibition Of TCR Signaling With Peptide Variants	SIGNABLOK, INC.	2022-08-18	—	—	US	claimed