SCHEMBL30607476

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CN)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.67

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.67

▸	VIPR2	P41587	7/20	0.66

▸	VIPR1	P32241	5/20	0.65

▸	GLP1R	P43220	4/20	0.61

▸	ECE1	P42892	1/20	0.61

▸	MUS81	Q96NY9	1/20	0.61

▸	NPY2R	P49146	6/20	0.59

▸	NPY4R	P50391	6/20	0.59

▸	NPY5R	Q15761	6/20	0.59

▸	NPY1R	P25929	4/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30435933	0.95	TFPI (0.71)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL30495775	0.94	VIPR1 (0.70)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL29634728	0.93	TFPI (0.61)	TFPIVIPR2VIPR1
SCHEMBL30495814	0.92	VIPR1 (0.71)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL30695558	0.92	TFPI (0.78)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL31517010	0.92	GLP1R (0.64)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL31563800	0.91	VIPR1 (0.73)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL31255288	0.91	TFPI (0.61)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL31182584	0.91	TFPI (0.66)	TFPIVIPR2VIPR1GLP1RECE1
SCHEMBL29407944	0.91	VIPR2 (0.62)	TFPIVIPR2VIPR1NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12383505-B2	Nanoparticle for the remodeling of cancer-associated fibroblasts	UNIVERSITY OF SOUTH CAROLINA (US)	2025-08-12	—	—	US	disclosed
US-20230310331-A1	NANOPARTICLE FOR THE REMODELING OF CANCER-ASSOCIATED FIBROBLASTS	UNIVERSITY OF SOUTH CAROLINA (US)	2023-10-05	—	—	US	disclosed