Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.61 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.61 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.51 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140591 | 1.00 | ITGAV (0.61) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20139714 | 0.93 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20139938 | 0.93 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20140538 | 0.93 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20139608 | 0.83 | ITGB3 (0.40) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL29797182 | 0.83 | ITGB3 (0.40) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20140195 | 0.83 | ITGAV (0.54) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL29797306 | 0.83 | ITGAV (0.54) | ITGAVITGB3ITGB6ITGA2BITGB5 | |
| SCHEMBL20142767 | 0.81 | ITGB3 (0.40) | ITGAVITGB3ITGB6ITGA2B | |
| SCHEMBL29797239 | 0.81 | ITGB3 (0.40) | ITGAVITGB3ITGB6ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | disclosed |