Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.67 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.67 |
| ▸ | ITGB6 | P18564 | 13/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.65 |
| ▸ | ITGB8 | P26012 | 10/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 9/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294658 | 1.00 | ITGAV (0.67) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL21294650 | 1.00 | ITGAV (0.67) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL20140348 | 1.00 | ITGAV (0.67) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL29797151 | 0.93 | ITGB3 (0.60) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL20140529 | 0.93 | ITGB3 (0.60) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL20141952 | 0.88 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL21294646 | 0.88 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL30850808 | 0.88 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL20141955 | 0.88 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL21294582 | 0.87 | ITGAV (0.64) | ITGAVITGB3ITGB6ITGA2BITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | disclosed |