Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 12/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139522 | 1.00 | CTSA (0.40) | CTSAPRKCZRAB9AITGB3ITGAV | |
| SCHEMBL20140402 | 0.81 | CTSA (0.41) | CTSAITGB3ITGAVITGB6FFAR1 | |
| SCHEMBL29797198 | 0.79 | FGFR2 (0.38) | CTSAPRKCZRAB9AITGB3ITGAV | |
| SCHEMBL20139722 | 0.79 | FGFR2 (0.38) | CTSAPRKCZRAB9AITGB3ITGAV | |
| SCHEMBL29797153 | 0.78 | CTSA (0.41) | CTSARAB9ANPC1FFAR1LMNA | |
| SCHEMBL20139502 | 0.78 | CTSA (0.41) | CTSARAB9ANPC1FFAR1LMNA | |
| SCHEMBL20380272 | 0.75 | FFAR1 (0.44) | PRKCZRAB9AFFAR1ALDH1A1LMNA | |
| SCHEMBL29797272 | 0.75 | ITGB3 (0.47) | CTSAPRKCZRAB9AITGB3ITGAV | |
| SCHEMBL20139498 | 0.75 | ITGB3 (0.47) | CTSAPRKCZRAB9AITGB3ITGAV | |
| SCHEMBL20139800 | 0.74 | ITGB3 (0.44) | CTSAPRKCZRAB9AITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-B | 3-substituted propionic acids as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-05-27 | — | — | CN | disclosed |