Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054273 | 1.00 | KDM4C (0.41) | KDM4CCDK5CDK5R1AXLPRKCI | |
| SCHEMBL21143892 | 0.79 | KDM4C (0.38) | KDM4CCDK5CDK5R1HDAC1HDAC6 | |
| SCHEMBL27920597 | 0.78 | CDK5 (0.46) | KDM4CCDK5CDK5R1HDAC1HDAC6 | |
| SCHEMBL442421 | 0.78 | KDM4C (0.46) | KDM4CCDK5CDK5R1AXLHDAC1 | |
| SCHEMBL28135746 | 0.75 | IDO1 (0.33) | AXLPRKCIIDO1MEN1KMT2A | |
| SCHEMBL30968240 | 0.74 | KDM4C (0.39) | KDM4CCDK5CDK5R1ABCB1ABCG2 | |
| SCHEMBL6535291 | 0.73 | TDP1 (0.44) | RPS6KA5RPS6KA4TDP1MEN1KMT2A | |
| SCHEMBL10498353 | 0.73 | KDM4C (0.34) | KDM4CCDK5CDK5R1HDAC1HDAC6 | |
| SCHEMBL5189834 | 0.72 | NISCH (0.42) | AXLPRKCIIDO1MEN1KMT2A | |
| SCHEMBL30968251 | 0.71 | KDM4C (0.47) | KDM4CCDK5CDK5R1PRKCIHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114727987-A | Substituted heterocyclic compounds having HIV therapeutic activity | 纽约血库公司 | 2022-07-08 | — | — | CN | disclosed |