Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.50 |
| ▸ | CTSD | P07339 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 3/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798178 | 0.95 | BACE1 (0.53) | BACE1CTSDMME | |
| SCHEMBL31720947 | 0.94 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL29378429 | 0.92 | MME (0.55) | BACE1CTSDMME | |
| SCHEMBL29483748 | 0.92 | MME (0.55) | BACE1CTSDMME | |
| SCHEMBL30063231 | 0.92 | ECE1 (0.47) | BACE1CTSDMME | |
| SCHEMBL29544149 | 0.91 | MME (0.56) | BACE1CTSDMME | |
| SCHEMBL30099600 | 0.91 | MME (0.56) | BACE1CTSDMME | |
| SCHEMBL30737580 | 0.91 | BACE1 (0.50) | BACE1CTSDMME | |
| SCHEMBL29798316 | 0.91 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL29549540 | 0.90 | BACE1 (0.52) | BACE1CTSDMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259265-A1 | Inhibitors and Use Thereof in Cancer Treatment | THE UNIVERSITY OF SYDNEY (AU) | 2022-08-18 | — | — | US | disclosed |