Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.52 |
| ▸ | CTSD | P07339 | 4/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720947 | 0.97 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL29798028 | 0.93 | BACE1 (0.57) | BACE1CTSDECE1 | |
| SCHEMBL28586133 | 0.91 | ALDH1A1 (0.50) | BACE1CTSDALDH1A1MAPTLAP3 | |
| SCHEMBL28586132 | 0.91 | ALDH1A1 (0.50) | BACE1CTSDALDH1A1MAPTLAP3 | |
| SCHEMBL9657142 | 0.91 | ALDH1A1 (0.53) | ECE1ALDH1A1MAPTLAP3 | |
| SCHEMBL29797982 | 0.91 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL29531766 | 0.90 | BACE1 (0.46) | BACE1CTSDECE1ALDH1A1MAPT | |
| SCHEMBL30814697 | 0.90 | BACE1 (0.48) | BACE1CTSDALDH1A1MAPTLAP3 | |
| SCHEMBL30737622 | 0.90 | ECE1 (0.56) | BACE1CTSDECE1 | |
| SCHEMBL29630774 | 0.90 | ECE1 (0.56) | BACE1CTSDECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |
| US-20220259265-A1 | Inhibitors and Use Thereof in Cancer Treatment | THE UNIVERSITY OF SYDNEY (AU) | 2022-08-18 | — | — | US | disclosed |