Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22663565 | 1.00 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22663552 | 0.91 | ALDH1A1 (0.51) | KDM4EALDH1A1KMT2ALMNATSHR | |
| SCHEMBL22663431 | 0.90 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL22663598 | 0.87 | SMN1; SMN2 (0.45) | ALDH1A1MAPTHPGDCYP3A4LMNA | |
| SCHEMBL22663594 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL22663564 | 0.85 | HPGD (0.48) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL29797823 | 0.85 | HPGD (0.48) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL22663590 | 0.82 | MAPT (0.43) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22663585 | 0.82 | TSHR (0.46) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22663560 | 0.80 | KCNA5 (0.40) | ALDH1A1MAPTKMT2ACYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220233549-A1 | METHOD FOR ALPHAVIRUS INHIBITION | VenatoRx Pharmaceuticals, Inc. | 2022-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220233549-A1 | METHOD FOR ALPHAVIRUS INHIBITION | EIF2AK2, CHIA, HAVCR2 | HSD17B10 2018/4885KDM4E 665/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.