Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782763 | 1.00 | TLR8 (0.34) | TLR8KMT2AALDH1A1MAPTGAA | |
| SCHEMBL782765 | 1.00 | TLR8 (0.34) | TLR8KMT2AALDH1A1MAPTGAA | |
| SCHEMBL805323 | 0.94 | TLR8 (0.34) | TLR8KMT2AALDH1A1MAPTGAA | |
| SCHEMBL781940 | 0.92 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTGAANPSR1 | |
| SCHEMBL781938 | 0.92 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTGAANPSR1 | |
| SCHEMBL14693120 | 0.92 | TLR8 (0.33) | TLR8KMT2AGABRDGABRA1GABRB1 | |
| SCHEMBL781747 | 0.88 | ALDH1A1 (0.35) | TLR8ALDH1A1ENPP2ATXN2 | |
| SCHEMBL29798818 | 0.88 | ALDH1A1 (0.35) | TLR8ALDH1A1ENPP2ATXN2 | |
| SCHEMBL29798819 | 0.88 | ALDH1A1 (0.35) | TLR8ALDH1A1ENPP2ATXN2 | |
| SCHEMBL781745 | 0.88 | ALDH1A1 (0.35) | TLR8ALDH1A1ENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840847-B | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2022-07-29 | — | — | CN | disclosed |