SCHEMBL29800152

SCHEMBL29800152

CCCCCCN1CC=Nc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
CES1 P23141 2/20 0.39
CDC25A P30304 2/20 0.39
HTT P42858 1/20 0.38
EEF2K O00418 1/20 0.37
SLC9A1 P19634 2/20 0.37
ALDH2 P05091 1/20 0.37
ALDH3A1 P30838 1/20 0.37
HTR1A P08908 1/20 0.37
CNR2 P34972 3/20 0.36
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497270 0.98 KDM4E (0.39) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL28252765 0.94 CYP1A2 (0.37) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL28252759 0.87 MEN1 (0.41) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL28140628 0.80 KDM4E (0.38) KDM4EMEN1KMT2AALDH1A1
SCHEMBL7353592 0.76 MEN1 (0.47) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL31202624 0.75 CYP1A2 (0.42) MEN1KMT2AALDH1A1CYP1A2CYP2D6
SCHEMBL29064917 0.75 POLB (0.38) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL6196442 0.74 MEN1 (0.45) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL7346424 0.74 ALDH1A1 (0.49) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL7065366 0.73 ALDH1A1 (0.50) KDM4ELMNAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920706-A Method for preparing 3-acyl-quinoxaline-2 (1H) -ketone by ball milling method 新乡市润宇新材料科技有限公司 2022-08-19 CN disclosed