Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TNKS | O95271 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293768 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| Hydrochloric Acid SCHEMBL23293837 | 0.99 | KDM4E (0.56) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| Succinic Acid SCHEMBL23293781 | 0.94 | KDM4E (0.51) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL23293858 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL27242014 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL29800591 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL23293821 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL23316314 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| Hydrochloric Acid SCHEMBL23293893 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1MAPTTNKSPARP1 | |
| SCHEMBL23293905 | 0.89 | STAT3 (0.49) | KDM4EALDH1A1MAPTTNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | claimed |
| US-20220287748-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR SPINAL MUSCULAR ATROPHY | REBORNA BIOSCIENCES, INC. (JP) | 2022-09-15 | — | — | US | claimed |
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-20220287748-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR SPINAL MUSCULAR ATROPHY | REBORNA BIOSCIENCES, INC. (JP) | 2022-09-15 | — | — | US | disclosed |