Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.93 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.63 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TOP1 | P11387 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793906 | 1.00 | MEN1 (0.93) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL21707396 | 0.98 | MEN1 (0.89) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL11675529 | 0.96 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL2385408 | 0.91 | KMT2A (0.83) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL3863282 | 0.91 | KMT2A (0.77) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL2063559 | 0.91 | KMT2A (0.77) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL28860008 | 0.90 | MEN1 (0.76) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL23070493 | 0.90 | MEN1 (0.75) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL11669212 | 0.88 | KCNK3 (0.81) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL10806300 | 0.88 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805112-A | PDE2 inhibitor amide derivative and preparation method thereof | 常州大学 | 2022-07-29 | — | — | CN | disclosed |