SCHEMBL2385408

SCHEMBL2385408

O=C(Nc1cccc(O)c1)c1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.83
MEN1 O00255 7/20 0.83
KCNK3 O14649 6/20 0.79
KCNK9 Q9NPC2 4/20 0.79
RAB9A P51151 6/20 0.73
NPC1 O15118 5/20 0.73
MAPK1 P28482 2/20 0.73
TP53 P04637 2/20 0.73
SIRT1 Q96EB6 1/20 0.69
MAPT P10636 3/20 0.69
LMNA P02545 2/20 0.69
HPGD P15428 1/20 0.67
POLB P06746 2/20 0.66
ALDH1A1 P00352 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
PKM P14618 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22589002 0.92 SIRT1 (0.79) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL29800565 0.91 MEN1 (0.93) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL11675529 0.91 MEN1 (1.00) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL6793906 0.91 MEN1 (0.93) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL28218534 0.91 KMT2A (0.69) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL2063559 0.89 KMT2A (0.77) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL21707396 0.89 MEN1 (0.89) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL3656361 0.89 NPC1 (0.78) KMT2AMEN1KCNK3KCNK9RAB9A
SCHEMBL2298254 0.88 KCNK3 (1.00) KMT2AMEN1KCNK3KCNK9RAB9A
N-Phenylbenzamide SCHEMBL27671345 0.86 POLB (0.71) KMT2AMEN1KCNK3KCNK9RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52116432-A None JP disclosed
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER SUMITOMO CHEMICAL CO (JP) 2026-01-01 US disclosed
EP-4578895-A1 POLYMER, RESIN COMPOSITION, MOLDED BODY, AND POLYMER PRODUCTION METHOD Sumitomo Chemical Company, Limited (JP) 2025-07-02 EP disclosed
EP-4578894-A1 HYDROPHILIC OIL REPELLENT POLYMER Sumitomo Chemical Company, Limited (JP) 2025-07-02 EP disclosed
CN-119604562-A Hydrophilic oil-repellent polymer 住友化学株式会社 2025-03-11 CN disclosed
WO-2024043326-A1 HYDROPHILIC OIL REPELLENT POLYMER 住友化学株式会社 2024-02-29 WO disclosed
WO-2024043327-A1 POLYMER, RESIN COMPOSITION, MOLDED BODY, AND POLYMER PRODUCTION METHOD 住友化学株式会社 2024-02-29 WO disclosed
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
EP-4130057-A1 HYDROPHILIC OIL REPELLENT POLYMER Sumitomo Chemical Company, Limited (JP) 2023-02-08 EP disclosed
WO-2022255400-A1 CLEANER FOR INDOOR WATER USE SITES 住友化学株式会社 2022-12-08 WO disclosed
US-20160031797-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF GTX, INC. 2016-02-04 US disclosed
WO-2014195507-A1 3-CARBOXY SUBSTITUTED COUMARIN DERIVATIVES WITH A POTENTIAL UTILITY FOR THE TREATMENT OF CANCER DISEASES UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2014-12-11 WO disclosed
US-8293715-B2 10a-Azalide compound crosslinked at 10a- and 12-positions TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-10-23 US disclosed
US-20110237784-A1 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2011-09-29 US disclosed
EP-2177526-A1 10A-AZALIDE COMPOUND CROSSLINKED AT POSITION-10A AND POSITION-12 Taisho Pharmaceutical Co. Ltd. (JP) 2010-04-21 EP disclosed
US-20070060607-A1 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives BARTKOVITZ DAVID J 2007-03-15 US disclosed
EP-1633715-A1 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS Pfizer Limited (GB) 2006-03-15 EP disclosed
WO-2004108676-A1 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS PFIZER LIMITED (GB) 2004-12-16 WO disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
JP-S52116432-A PREPARATION OF 3-ALKOXYBENZANILIDES KUMIAI CHEM IND CO LTD 1977-09-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237784-A1 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS DCLRE1A, AZI2, CHD9 KMT2A 568/4885MEN1 3118/4885KCNK3 3756/4885
US-20160031797-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF ESRRB, ESRRA, ESR2 KMT2A 2272/4885MEN1 3937/4885KCNK3 3604/4885
US-20070060607-A1 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives BRAF, RAF1, MAP3K7 KMT2A 1605/4885MEN1 1791/4885KCNK3 2318/4885
US-20260001999-A1 HYDROPHILIC OIL REPELLENT POLYMER CCR1, H1-3, CCR3 KMT2A 1993/4885MEN1 1349/4885KCNK3 2814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.