Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120229 | 1.00 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5188552 | 0.87 | MAPT (0.67) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL29777337 | 0.87 | MAPT (0.67) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7478482 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL4642926 | 0.80 | MEN1 (0.67) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL317836 | 0.80 | KMT2A (1.00) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL6538214 | 0.80 | MAPT (0.77) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL31067265 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL4865525 | 0.79 | MEN1 (0.57) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL34471923 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |