Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26964231 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL29069665 | 0.80 | APP (0.42) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL26964284 | 0.79 | APP (0.44) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL26964234 | 0.77 | TP53 (0.53) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL2099509 | 0.76 | TP53 (0.52) | SMN1; SMN2ALDH1A1APPTP53TDP1 | |
| SCHEMBL16334065 | 0.76 | TP53 (0.52) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL16334362 | 0.75 | TP53 (0.51) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL29661774 | 0.73 | MAOB (0.52) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL190495 | 0.73 | MAOB (0.52) | SMN1; SMN2ALDH1A1LMNAAPPTP53 | |
| SCHEMBL27595525 | 0.73 | MAPT (0.50) | SMN1; SMN2LMNAAPPTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291555-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116806218-A | Sulfonamide and its use for the treatment of parasitic helminth infections and diseases | 新基公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022173727-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-08-18 | — | — | WO | disclosed |