Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HPGDS | O60760 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975342 | 1.00 | HTT (0.61) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL24975354 | 0.90 | HTT (0.77) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL29996180 | 0.89 | HTT (0.72) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL23063861 | 0.89 | HTT (0.72) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL29801317 | 0.84 | HTT (0.58) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL24976313 | 0.84 | HTT (0.58) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL29801122 | 0.83 | KMT2A (0.66) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL24975530 | 0.83 | HPGDS (0.64) | HTTALDH1A1LMNAKMT2AHPGDS | |
| SCHEMBL24975558 | 0.83 | KMT2A (0.66) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29801099 | 0.83 | HPGDS (0.64) | HTTALDH1A1LMNAKMT2AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930509-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114929672-B | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |