Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754201 | 1.00 | FFAR1 (0.44) | FFAR1PDE10AIRAK4TRPV3HCRTR1 | |
| SCHEMBL16754205 | 0.81 | PDE10A (0.45) | PDE10ATRPV3HCRTR1HCRTR2 | |
| SCHEMBL29801610 | 0.81 | PDE10A (0.45) | PDE10ATRPV3HCRTR1HCRTR2 | |
| SCHEMBL15885161 | 0.81 | FFAR1 (0.50) | FFAR1IRAK4 | |
| SCHEMBL17247588 | 0.80 | FFAR1 (0.52) | FFAR1IRAK4 | |
| SCHEMBL14857490 | 0.79 | PDE10A (0.42) | PDE10ATRPV3HCRTR1HCRTR2 | |
| SCHEMBL29801219 | 0.79 | PDE10A (0.42) | PDE10ATRPV3HCRTR1HCRTR2 | |
| SCHEMBL15885095 | 0.78 | FFAR1 (0.47) | FFAR1IRAK4 | |
| SCHEMBL18996856 | 0.77 | FFAR1 (0.49) | FFAR1IRAK4 | |
| SCHEMBL20401337 | 0.76 | FFAR1 (0.51) | FFAR1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535155-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2022-07-12 | — | — | CN | disclosed |