SCHEMBL20401337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17247588	0.83	FFAR1 (0.52)	FFAR1KLKB1HDAC1HDAC2IRAK4
	SCHEMBL15885161	0.82	FFAR1 (0.50)	FFAR1KLKB1HDAC1HDAC2IRAK4
	SCHEMBL20401265	0.80	FFAR1 (0.57)	FFAR1KLKB1IRAK4DGAT1
	SCHEMBL15885095	0.79	FFAR1 (0.47)	FFAR1KLKB1IRAK4LIPGTAS2R8
	SCHEMBL18996856	0.78	FFAR1 (0.49)	FFAR1KLKB1IRAK4LIPGTAS2R8
	SCHEMBL20436375	0.78	HDAC1 (0.42)	KLKB1HDAC1HDAC2IRAK4TAS2R8
	SCHEMBL2825716	0.77	KLKB1 (0.46)	KLKB1HDAC1HDAC2IRAK4
	SCHEMBL20416533	0.77	HDAC1 (0.39)	KLKB1HDAC1HDAC2IRAK4TAS2R8
	SCHEMBL16754201	0.76	FFAR1 (0.44)	FFAR1IRAK4
	SCHEMBL29801233	0.76	FFAR1 (0.44)	FFAR1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.