Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932292 | 1.00 | CASP3 (0.63) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL26932181 | 0.91 | CASP3 (0.65) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL29802515 | 0.91 | CASP3 (0.65) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL26932351 | 0.84 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL29802413 | 0.84 | CASP3 (0.61) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL29802321 | 0.83 | CASP3 (0.67) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL26932215 | 0.83 | CASP3 (0.70) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL26932174 | 0.83 | CASP3 (0.67) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL29802104 | 0.83 | CASP3 (0.70) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL29802090 | 0.83 | CASP3 (0.70) | CASP3SENP8SENP7SENP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805236-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114805236-A | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2022-07-29 | — | — | CN | disclosed |