Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.76 |
| ▸ | NPC1 | O15118 | 11/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 12/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932212 | 1.00 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29802302 | 0.88 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26932335 | 0.88 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26932329 | 0.84 | SMN1; SMN2 (0.76) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL29802208 | 0.84 | SMN1; SMN2 (0.76) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL29802254 | 0.82 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26932346 | 0.82 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29802119 | 0.81 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29802112 | 0.81 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26932242 | 0.81 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805236-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114805236-A | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2022-07-29 | — | — | CN | disclosed |