Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932287 | 1.00 | CASP3 (0.69) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL29802221 | 0.87 | CASP3 (0.73) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL26932280 | 0.87 | CASP3 (0.73) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL29802127 | 0.86 | CASP3 (0.65) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL26932246 | 0.86 | CASP3 (0.65) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL29802113 | 0.86 | CASP3 (0.65) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL26932203 | 0.86 | CASP3 (0.65) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL29802104 | 0.85 | CASP3 (0.70) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL26932215 | 0.85 | CASP3 (0.70) | CASP3SENP8SENP7SENP6NAMPT | |
| SCHEMBL29802413 | 0.84 | CASP3 (0.61) | CASP3SENP8SENP7SENP6NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805236-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114805236-A | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2022-07-29 | — | — | CN | disclosed |