Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432579 | 0.86 | REN (0.51) | RENACE2ESR1PTPN1ESR2 | |
| SCHEMBL29310044 | 0.82 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL29689144 | 0.81 | REN (0.48) | RENACE2ESR1PTPN1ESR2 | |
| SCHEMBL29883039 | 0.79 | CYP3A4 (0.48) | RENPTPN1SLC15A2 | |
| SCHEMBL21529460 | 0.75 | REN (0.46) | RENACE2ESR1SLC15A2 | |
| SCHEMBL28354383 | 0.75 | REN (0.46) | RENACE2ESR1SLC15A2 | |
| SCHEMBL24462463 | 0.74 | REN (0.74) | RENACE2PTPN1NPY4R | |
| SCHEMBL29310045 | 0.74 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL18402423 | 0.74 | REN (0.60) | RENACE2SLC15A2 | |
| SCHEMBL31094977 | 0.73 | PTPN1 (0.46) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12133720-B2 | Methods and compositions for restoring homeostatic capacity of a subject | Palo Alto Investors LP (US) | 2024-11-05 | — | — | US | disclosed |
| WO-2022190064-A1 | METHODS FOR IDENTIFYING SUBJECTS WITH BETACORONAVIRUS INFECTIONS WHO ARE AT RISK OF ACUTE RESPIRATORY SYNDROME AND METHODS FOR THE TREATMENT OF SAME | VEXO PHARMACEUTICALS DMCC (AE) | 2022-09-15 | — | — | WO | disclosed |
| CN-113106147-B | Three-dimensional DNA nano machine driven by exonuclease III and application thereof | 山东师范大学 | 2022-08-02 | — | — | CN | disclosed |