Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | DDX3X | O00571 | 3/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26932331 | 1.00 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2DDX3XIMPDH2 | |
| SCHEMBL29802254 | 0.85 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL26932346 | 0.85 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL26932304 | 0.84 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL29802124 | 0.84 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL29802244 | 0.83 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2IMPDH2MAPT | |
| SCHEMBL26932197 | 0.83 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2IMPDH2MAPT | |
| SCHEMBL29802208 | 0.82 | SMN1; SMN2 (0.76) | RAB9ANPC1SMN1; SMN2IMPDH2KMT2A | |
| SCHEMBL26932329 | 0.82 | SMN1; SMN2 (0.76) | RAB9ANPC1SMN1; SMN2IMPDH2KMT2A | |
| SCHEMBL29802081 | 0.82 | NPC1 (0.67) | RAB9ANPC1SMN1; SMN2DDX3XKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805236-B | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114805236-A | Benzoxazole derivative and preparation method and application thereof | 苏州大学 | 2022-07-29 | — | — | CN | disclosed |