Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.62 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | NPY4R | P50391 | 1/20 | 0.62 |
| ▸ | MME | P08473 | 2/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | CPA1 | P15085 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792483 | 1.00 | ACE (0.67) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL29822758 | 0.96 | FOLH1 (0.66) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL30123084 | 0.96 | ACE (0.62) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL30051537 | 0.94 | LTA4H (0.61) | ACEMMECPA1ACE2 | |
| SCHEMBL31067318 | 0.94 | FOLH1 (0.69) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL2474675 | 0.94 | FOLH1 (0.69) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL11056714 | 0.94 | FOLH1 (0.69) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL29734944 | 0.93 | FOLH1 (0.68) | ACEFOLH1NPY1RNPY2RNPY4R | |
| SCHEMBL29350874 | 0.93 | FOLH1 (0.68) | ACEFOLH1NPY1RNPY2RNPY4R | |
| Hydrochloric Acid SCHEMBL6473764 | 0.93 | FOLH1 (0.67) | ACEFOLH1NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022190064-A1 | METHODS FOR IDENTIFYING SUBJECTS WITH BETACORONAVIRUS INFECTIONS WHO ARE AT RISK OF ACUTE RESPIRATORY SYNDROME AND METHODS FOR THE TREATMENT OF SAME | VEXO PHARMACEUTICALS DMCC (AE) | 2022-09-15 | — | — | WO | disclosed |