Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671078 | 1.00 | TRPV1 (0.40) | TRPV1TMPRSS2MAPTHTTLMNA | |
| Trifluoroacetic Acid SCHEMBL29803374 | 0.95 | TRPV1 (0.40) | TRPV1TMPRSS2MAPTHTTLMNA | |
| SCHEMBL24669917 | 0.88 | ALDH1A1 (0.44) | TMPRSS2MAPTHTTLMNAALDH1A1 | |
| SCHEMBL29802919 | 0.86 | TMPRSS2 (0.42) | TRPV1TMPRSS2MAPTHTTLMNA | |
| SCHEMBL24670481 | 0.86 | TMPRSS2 (0.42) | TRPV1TMPRSS2MAPTHTTLMNA | |
| SCHEMBL24669235 | 0.86 | TRPV1 (0.41) | TRPV1TMPRSS2MAPT | |
| SCHEMBL29802980 | 0.86 | TRPV1 (0.41) | TRPV1TMPRSS2MAPT | |
| Trifluoroacetic Acid SCHEMBL29803766 | 0.84 | ALDH1A1 (0.42) | TRPV1TMPRSS2MAPTHTTLMNA | |
| SCHEMBL24670476 | 0.84 | NAMPT (0.49) | NAMPT | |
| SCHEMBL29803259 | 0.84 | NAMPT (0.49) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |