⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491193 | 0.85 | — | — | |
| SCHEMBL2344125 | 0.81 | — | — | |
| SCHEMBL3341894 | 0.81 | — | — | |
| SCHEMBL455963 | 0.81 | — | — | |
| SCHEMBL11448327 | 0.81 | — | — | |
| SCHEMBL456834 | 0.77 | — | — | |
| SCHEMBL1424328 | 0.77 | ACHE (0.39) | — | |
| SCHEMBL17514755 | 0.74 | TYMP (0.34) | — | |
| SCHEMBL11458412 | 0.74 | TSHR (0.45) | — | |
| SCHEMBL58386 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2019-10-15 | — | — | US | claimed |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-05-31 | — | — | US | claimed |
| CN-105797774-A | Novel linear alpha-olefin catalyst and preparation and industrial application thereof | 亚培烯科技(嘉兴)有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105797773-A | Novel linear alpha-olefin catalyst and preparation technology and application thereof | 亚培烯科技(嘉兴)有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105728045-A | Novel linear alpha olefin catalyst and preparation method and application thereof | 亚培烯科技(嘉兴)有限公司 | 2016-07-06 | — | — | CN | claimed |
| US-8343968-B2 | Case of renin inhibitors | MERCK CANADA INC. (CA) | 2013-01-01 | — | — | US | claimed |
| EP-2376473-A1 | 3,4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Merck Canada Inc. (CA) | 2011-10-19 | — | — | EP | claimed |
| US-20110237622-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2011-09-29 | — | — | US | claimed |
| WO-2010066028-A1 | 3,4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2010-06-17 | — | — | WO | claimed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | claimed |
| EP-0805677-B1 | EXTENDED RELEASE CLONIDINE FORMULATION | HORACEK H JOSEPH (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2001007491-A1 | METHOD FOR PREPARING OLEFIN (CO)POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | claimed |
| EP-0256798-B1 | ANAESTHETIC COMPOSITION | Anaquest, Inc. (US) | 1991-09-25 | — | — | EP | claimed |
| US-4859685-A | Anesthetic composition and method of using the same | BOC, INC. (US) | 1989-08-22 | — | — | US | claimed |
| EP-0256798-A1 | Anaesthetic composition | Anaquest, Inc. (US) | 1988-02-24 | — | — | EP | claimed |
| US-4514490-A | COLORFASTNESS; COUPLER WITH METHYLENEDIOAY BENZENE GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-30 | — | — | US | claimed |
| US-4336325-A | CONTAING A MAGENTA COLOR-FORMING COUPLER WHICH PREVENTS YELLOW STAIN | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-22 | — | — | US | claimed |
| US-4163670-A | PYRAZOLONE COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-08-07 | — | — | US | claimed |
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | claimed |