Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670286 | 0.80 | CCNT1 (0.48) | MAPKAPK2NAMPTNPC1RAB9AMELK | |
| SCHEMBL29803746 | 0.80 | CCNT1 (0.42) | MAPKAPK2NAMPTSIGMAR1HTR2CFTO | |
| SCHEMBL24670573 | 0.80 | MAPKAPK2 (0.59) | MAPKAPK2SLC2A1NAMPTSIGMAR1HTR2C | |
| SCHEMBL29803346 | 0.76 | NAMPT (0.51) | MAPKAPK2SLC2A1NAMPTHTR2CQDPR | |
| SCHEMBL29803785 | 0.76 | CCNT1 (0.47) | MAPKAPK2SLC2A1NPC1RAB9AMELK | |
| SCHEMBL29803253 | 0.76 | CCNT1 (0.47) | HTR2CMELKCCNT1CDK9 | |
| SCHEMBL24671563 | 0.76 | TMPRSS2 (0.46) | NAMPTNPC1RAB9ATP53MAPT | |
| SCHEMBL29802889 | 0.76 | TMPRSS2 (0.46) | NAMPTNPC1RAB9ATP53MAPT | |
| SCHEMBL24670537 | 0.75 | MAPKAPK2 (0.45) | MAPKAPK2NAMPTSIGMAR1HTR2CFTO | |
| SCHEMBL29803753 | 0.74 | CCNT1 (0.45) | MAPKAPK2NAMPTSIGMAR1HTR2CFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |