Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | QDPR | P09417 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | MELK | Q14680 | 2/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892281 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL29803255 | 0.90 | MAPKAPK2 (0.56) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL29803788 | 0.88 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTQDPRSLC2A1 | |
| SCHEMBL30182258 | 0.88 | SLC2A1 (0.60) | MAPKAPK2NAMPTSLC2A1MELK | |
| SCHEMBL24671331 | 0.88 | NAMPT (0.51) | MAPKAPK2NAMPT | |
| SCHEMBL24891957 | 0.88 | SLC2A1 (0.60) | MAPKAPK2NAMPTSLC2A1MELK | |
| SCHEMBL30182307 | 0.87 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTQDPRSIGMAR1 | |
| SCHEMBL24891839 | 0.87 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTQDPRSIGMAR1 | |
| SCHEMBL24891639 | 0.86 | MAPKAPK2 (0.53) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL24669402 | 0.86 | SLC2A1 (0.61) | MAPKAPK2NAMPTSLC2A1MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |