Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891728 | 0.89 | NAMPT (0.46) | NAMPTKDM4EALDH1A1GLAMAPT | |
| SCHEMBL29803678 | 0.88 | NAMPT (0.42) | NAMPTKDM4EALDH1A1GLAMAPT | |
| SCHEMBL24669300 | 0.88 | NAMPT (0.42) | NAMPTKDM4EALDH1A1GLAMAPT | |
| SCHEMBL29803599 | 0.87 | NAMPT (0.41) | NAMPTKDM4EALDH1A1GLAMAPT | |
| SCHEMBL24670218 | 0.87 | NAMPT (0.46) | NAMPT | |
| SCHEMBL24670217 | 0.87 | NAMPT (0.46) | NAMPT | |
| SCHEMBL29803536 | 0.86 | NAMPT (0.40) | NAMPTMAPT | |
| SCHEMBL29803469 | 0.86 | NAMPT (0.44) | NAMPTKDM4E | |
| SCHEMBL24670210 | 0.86 | NAMPT (0.44) | NAMPTKDM4E | |
| SCHEMBL29803348 | 0.86 | NAMPT (0.46) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |